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Spanish National Cancer Research Centre (CNIO)

Spanish National Cancer Research Centre (CNIO)

Research Institution

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The race to drug KRAS in pancreatic cancer

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PNAS paper retracted April 2026 for undisclosed competing interests; triple-therapy research ongoing with paper resubmitted for independent peer review

In April 2026, daraxonrasib became the first drug to beat chemotherapy in a Phase 3 pancreatic cancer trial, cutting death risk by 60% and extending median survival from 6.7 to 13.2 months. The FDA authorized expanded access May 1; Revolution Medicines plans to file a New Drug Application and present full Phase 3 data at the ASCO Annual Meeting on May 31, 2026.

Updated 5 days ago