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Regeneron Pharmaceuticals

Regeneron Pharmaceuticals

Pharmaceutical company

Appears in 6 stories

Stories

Sanofi pays Regeneron $1 billion upfront to expand Dupixent alliance

Money Moves

Invented the four new antibodies; leads research and development

Sanofi's biggest product is running out of room. Dupixent, the anti-inflammation antibody it co-developed with Regeneron, brought in $17.8 billion in 2025—roughly 36% of the French company's sales—and a key US patent expires in 2031.

Updated Oct 3

Gene therapy restores hearing in deaf patients

New Capabilities

Otarmeni approved by FDA in April 2026; provided free to eligible US patients

A single injection into the inner ear can now restore hearing in children born deaf. In April 2026 the FDA approved Otarmeni, the first gene therapy for inherited hearing loss, after about 80% of 24 trial participants gained measurable hearing and 42% could pick up whispers.

Updated Oct 3

Olatorepatide Phase III data show 19.3% weight loss with low nausea rates

New Capabilities

Holds exclusive olatorepatide rights outside Greater China; planning global registrational program

Hansoh Pharma presented full Phase III results for olatorepatide at the European Association for the Study of Diabetes meeting in Milan on October 2. Overweight and obese patients on the highest 15 mg dose lost 19.3% of their body weight on average by week 48, and the weight-loss curve had not flattened.

Updated Oct 2

Kodiak eye drug matches Eylea in phase 3 trial after 2023 safety halt

New Capabilities

Maker of Eylea, the comparator in the DAYBREAK trial

A drug Kodiak Sciences shelved in 2023 after a cataract safety signal is now on track for an FDA filing. The company reported Monday that both its experimental therapies for wet age-related macular degeneration met their primary endpoints against Regeneron's standard-of-care Eylea in the Phase 3 DAYBREAK trial.

Updated Sep 29

Intellia releases first Phase 3 readout for an in-body CRISPR therapy

New Capabilities

Co-development and royalty partner on lonvo-z

On April 27, 2026, Intellia Therapeutics reported results from Phase 3 testing of lonvoguran ziclumeran (lonvo-z), a one-time in-body CRISPR gene-editing therapy for hereditary angioedema. The 80-patient randomized double-blind trial found a single IV infusion cut debilitating swelling attack rates by 87% versus placebo (weeks 5-28); 62% of patients became attack-free and stopped all preventive medications. The safety profile was clean: no serious adverse events, and infusion-related reactions, headache, and fatigue—the most common complaints—were mild or moderate.

Updated May 31

Dupixent becomes one of the most versatile drugs in pharmaceutical history

New Capabilities

Co-developer and co-marketer of Dupixent; 74% of revenue dependent on key biologic drugs

Dupixent was approved for severe eczema in 2017 as a one-disease drug. Nine years later, it's approved for nine conditions, with the latest approval (February 24, 2026) covering allergic fungal rhinosinusitis (AFRS) — which previously had no approved treatment — and reducing the need for additional surgeries and steroid courses by 92% in trials.

Updated May 29