United Nations Office on Drugs and Crime (UNODC) — Laboratory and Scientific Service

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The U.S. closes the legal door on 4-CMC—five years after the UN did

Published early-warning and scheduling-entered-into-force notices covering 4-CMC

4-CMC is one of those modern drug-market products built for speed: cheap, tweakable chemistry that can be sold as a "new" stimulant the moment the old one gets banned. On December 17, 2025, the U.S. finally snapped the trap shut—DEA's Schedule I controls for 4-CMC took effect nationwide.

Updated May 15