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Vanderbilt BioVU

Vanderbilt BioVU

DNA Biobank

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MSI2 protective variant against blood cancer discovered

New Capabilities

Provided longitudinal validation data

For decades, cancer genetics meant finding mutations that raise risk. Now scientists have found one that lowers it. A variant in the MSI2 gene reduces the risk of blood cancers by up to 30% in people who carry two copiesโ€”the first protective genetic variant identified against myeloid malignancies.

Updated Jan 28