Lead researcher; Professor and Chief of Pediatric Infectious Diseases, UC San Diego School of Medicine
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Leading preclinical development of selective acne vaccine
Nearly a billion people worldwide have acne, and for decades, the best medicine could offer was topical creams that irritate skin, antibiotics that breed resistance, or a powerful drug — isotretinoin — that causes birth defects. On December 5, 2023, researchers at UC San Diego published a finding that reframes the problem entirely: the bacterium living on every human face produces two versions of the same enzyme, and which version dominates determines whether skin stays clear or breaks out.
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