Hansruedi Mathys

Senior author of the Science study; assistant professor, University of Pittsburgh School of Medicine

Appears in 1 story

Last updated Sep 13, 2026

Stories

Alzheimer's disrupts the 3D folding of DNA in brain cells

New Capabilities

As of September 2026: Leading follow-up research on genome architecture in Alzheimer's

Alzheimer's disease scrambles the three-dimensional folding of DNA inside brain cells, a study published in Science on July 23 reports. It's the first single-cell map of how the disease reshapes the genome's architecture across the brain.

Updated Sep 13