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Jahangir Hossain

Jahangir Hossain

Lead Author, Phase 2b Trial

Appears in 1 story

Stories

First vaccine against childhood E. coli diarrhea advances toward global use

New Capabilities

Principal investigator at MRC Gambia

Enterotoxigenic Escherichia coli, or ETEC, causes roughly 220 million episodes of diarrhea each year and kills tens of thousands of children under fiveโ€”mostly in low-income countries where clean water remains scarce. No vaccine against it has ever been licensed. On February 16, 2026, results published in The Lancet Infectious Diseases showed that an oral vaccine called ETVAX cut moderate-to-severe ETEC diarrhea by 48 percent in nearly 5,000 Gambian children, and by 68 percent in infants vaccinated before nine months of age.

Updated 21 hours ago