John Ioannidis

New Capabilities

Foundational figure in metascience; not directly involved in SCORE

For decades, social science findings shaped everything from classroom teaching methods to criminal sentencing guidelines—yet no one had systematically checked whether those findings held up. Now the results are in. A seven-year project involving 865 researchers, nearly 3,900 papers, and 62 journals across 11 disciplines found that only about 55% of published claims successfully replicate, and just 54% of studies are precisely computationally reproducible. The project, called SCORE and funded by the United States Defense Advanced Research Projects Agency (DARPA), is the largest and most comprehensive assessment of research reliability ever conducted. Within 24 hours of publication on April 2, major research funders began citing the findings to justify tightening data-sharing and pre-registration requirements.

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