Marina Chiara Garassino

Thoracic oncologist and lung cancer researcher, University of Chicago

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Lilly's olomorasib shows durable first-line activity in KRAS G12C lung cancer at ESMO

Argued first-line adoption by 2026 was unlikely without mature Phase 3 data

KRAS G12C-mutant non-small cell lung cancer has no approved first-line targeted therapy. Standard care is immunotherapy with or without chemotherapy, and because most patients never reach second-line treatment, the first choice is decisive.

Updated 3 hours ago