Paolo Ascierto

Professor, University of Naples Federico II; President, Melanoma Foundation

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HDAC inhibitor plus nivolumab cuts melanoma progression risk by 27% in Phase 3 trial

Key author of the Phase 3 study

A twice-weekly pill that strips melanoma cells of their camouflage extended progression-free survival by more than four months when added to the standard immunotherapy nivolumab. The Phase 3 result, presented at the European Society for Medical Oncology (ESMO) congress in Madrid, cut the risk of disease progression or death by 27%.

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