Uri Alon

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Study of 300 million lab tests finds menopause triggers abrupt body-wide changes

Leading the research team; preparing a randomized trial of pre-menopause hormone therapy

Menopause has long been treated as a slow, gradual shutdown of reproduction. A new analysis of 300 million laboratory tests from more than a million women in the United States and Israel argues the reality is sharper: a sudden, body-wide step change at the final menstrual period.

Updated 1 hour ago

Notable Quotes

Nowadays people check bone density around age 60, but this study would advocate checking around age 40 or 45 and then considering menopausal hormone therapy as prevention.

from Study of 300 million lab tests finds menopause triggers abrupt body-wide changes · Updated 1 hour ago

FSH and estradiol are not good enough to detect the exact moment of menopause because of the large fluctuations of perimenopause. It's still an unresolved problem.

from Study of 300 million lab tests finds menopause triggers abrupt body-wide changes · Updated 1 hour ago

Nothing can replace a randomized clinical trial.

from Study of 300 million lab tests finds menopause triggers abrupt body-wide changes · Updated 1 hour ago