Bonito Biosciences

New Capabilities

Launch customer focused on CNS therapies

Antibody discovery has long been a matter of trial and error: sequence millions of candidates, sort them by rough sequence similarity, then pay to test the most plausible few in the lab. On October 1, DaltonTx launched a platform called Dalton that tries to collapse that funnel. It folds antibody structures at a rate of 87,000 per hour—recently folding all 2.6 million paired antibody sequences in the OAS database—so researchers can compare candidates by actual 3D shape rather than amino-acid sequence alone.

Updated Yesterday