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The Carter Center

Nonprofit Organization

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The 40-year campaign to eradicate Guinea worm disease

New Capabilities

Leading global Guinea worm eradication campaign

In 1986, Guinea worm disease afflicted 3.5 million people annually across 21 nations. In 2025, only 10 human cases were recorded worldwide—the lowest number ever. If eradication succeeds, Guinea worm will become the second human disease eliminated globally after smallpox, and the first conquered without any medicine or vaccine.

Updated Feb 2