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Phase 1 complete in 88 participants with no dose-limiting toxicities; Phase 2b sarcopenia enrollment planned H2 2026; FDA Fast Track Designation application due Q2 2026 (decision pending); preclinical IBD program (MF-300 and MF-1305) active
A November 2025 study in Science showed that blocking an enzyme called 15-PGDH regrew cartilage in older mice and in human joint tissue from knee replacement patients. Blocking it shifts cartilage cells from degrading to rebuilding—without stem cells.
Updated Jun 13
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