Harvard Medical School

New Capabilities

Affiliation of McCarroll and Berretta

Huntington's disease has long been framed as a protein problem: mutant huntingtin clumps inside neurons and kills them. A new Cell study maps 428,173 cortical cells and finds that the neurons most likely to die carry extreme somatic expansions of the CAG repeat, beyond 450 repeats.

Updated 3 hours ago

New Capabilities

As of September 2026: Research home of the study's lead author

A heart from an older donor appears to shed its age after transplant into a younger patient. Within months its DNA methylation pattern — a molecular measure of accumulated cellular wear — realigns to the recipient's biological age.

Updated Sep 28

New Capabilities

As of September 2026: Research collaborator

Insilico Medicine opened its aging-research AI toolkit to anyone on September 17, 2026. The Cell cover study released LongevityBench, a 17-task benchmark for aging biology, plus Longevity-LLMs, five compact open-source language models trained on multi-omics data (genomics, proteomics, and other biological layers).

Updated Sep 18