PsychAD Consortium

New Capabilities

As of September 2026: Produced the lifespan atlas and the broader 1,494-donor cell reference

Scientists have mapped how every major cell type in the human prefrontal cortex changes across the entire lifespan — from birth to age 97. The atlas, published in Nature on September 23, 2026, profiles 1.3 million nuclei from 284 neurotypical donors and reveals that the brain's molecular activity proceeds in three distinct acts: intense remodeling through adolescence, relative stability through midlife, and a late-life surge of change concentrated in glial cells.

Updated Sep 25