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Rhythm Pharmaceuticals

Rhythm Pharmaceuticals

Biopharmaceutical Company

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FDA expands treatment options for obesity with rare and mainstream drug approvals

New Capabilities

Imcivree launches in largest indication; monitors GLP-1 competition in obesity space

For the first time, patients with acquired hypothalamic obesity have an FDA-approved treatment. On March 19, 2026, the FDA approved Imcivree (setmelanotide), which targets this rare condition affecting roughly 10,000 Americans whose hypothalamic damage from brain tumor surgery makes diet and exercise ineffective.

Updated May 30