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Sanford Burnham Prebys Medical Discovery Institute

Sanford Burnham Prebys Medical Discovery Institute

Nonprofit biomedical research institute

Appears in 1 story

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SORLA protein shown to reverse tau damage in Alzheimer's mouse models

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Institution behind the SORLA-tau research

For decades, Alzheimer's research chased plaques and tangles as things to clear away. A team in La Jolla, California took the opposite angle: boost a defense the brain already has. On July 17, 2026, they reported that raising levels of a protein called SORLA reversed tau damage in aged mice.

Updated Yesterday