SORLA protein shown to reverse tau damage in Alzheimer's mouse models

1879 - 1955

German-born theoretical physicist who developed the theory of relativity. Nobel laureate and one of the most influential scientists of all time.

1842 - 1914

American journalist and short story writer, author of The Devil's Dictionary. Known as 'Bitter Bierce' for his sardonic style.

1835 - 1919

Scottish-American industrialist who led the expansion of the American steel industry. One of the richest Americans in history and a major philanthropist.

1855 - 1937

American banker, industrialist, and philanthropist who served as Secretary of the Treasury. Founded the National Gallery of Art.

1905 - 1982

Russian-American novelist and philosopher, creator of Objectivism. Author of The Fountainhead and Atlas Shrugged, championing individualism and rational self-interest.

1706 - 1790

American polymath, Founding Father, author, scientist, and diplomat. Known for Poor Richard's Almanack and pioneering experiments with electricity.

1853 - 1902

British mining magnate and politician in Southern Africa. Founded De Beers and the Rhodes Scholarship. Controversial imperialist figure.

1809 - 1882

English naturalist who developed the theory of evolution by natural selection. Author of On the Origin of Species, one of the most influential works in scientific history.

1794 - 1877

American business magnate who built his wealth in railroads and shipping. Known as the Commodore, he was one of the richest Americans in history.

1893 - 1967

American poet, writer, and critic. Known for her biting wit and sharp-tongued reviews.

1884 - 1962

American political figure, diplomat, and activist. First Lady, chair of UN Human Rights Commission. Champion of civil rights and human dignity.

1818 - 1895

American social reformer, abolitionist, orator, and statesman. Escaped slave who became the most influential Black American of the 19th century.

1874 - 1936

English writer, philosopher, and Christian apologist. Author of the Father Brown mysteries and Orthodoxy. Master of paradox.

1903 - 1950

English novelist and essayist, author of 1984 and Animal Farm. Known for his lucid prose and opposition to totalitarianism.

1880 - 1956

American journalist and cultural critic, known as the 'Sage of Baltimore.' Relentless critic of American life and democracy.

1906 - 1975

German-American political theorist. Author of The Origins of Totalitarianism and Eichmann in Jerusalem. Analyzed totalitarianism and the banality of evil.

1837 - 1913

American financier and banker who dominated corporate finance on Wall Street. Founded J.P. Morgan & Co. and reorganized major railroads and corporations.

1924 - 1987

American novelist and social critic. Author of The Fire Next Time and Notes of a Native Son. Eloquent witness to racial injustice in America.

1839 - 1904

Indian industrialist and founder of the Tata Group. Pioneer of Indian industrialization who built steel, hospitality, and power enterprises.

1860 - 1935

American social reformer and Nobel Peace Prize laureate. Founded Hull House and championed immigrant rights.

1632 - 1704

English philosopher whose "Two Treatises of Government" (1689) profoundly influenced the American founders. Champion of natural rights, limited government, and the consent of the governed. Father of c...

1667 - 1745

Anglo-Irish satirist, author of Gulliver's Travels and A Modest Proposal. Master of sustained ironic argument.

1867 - 1919

First female self-made millionaire in America. Built a hair care empire and was a philanthropist and activist for Black causes.

1835 - 1910

American writer and humorist, author of The Adventures of Tom Sawyer and Adventures of Huckleberry Finn.

1759 - 1797

English writer and philosopher. Author of A Vindication of the Rights of Woman, pioneering advocate for women's equality and education.

1469 - 1527

Italian diplomat and political philosopher, author of The Prince. Analyzed power without moral illusion.

1854 - 1900

Irish poet and playwright, author of The Importance of Being Earnest. The most quotable writer in English.

1907 - 1964

American marine biologist and conservationist whose book Silent Spring sparked the modern environmental movement. Challenged the chemical industry and government complacency.

1709 - 1784

English writer, lexicographer, and critic. Author of A Dictionary of the English Language and countless memorable maxims.

1909 - 1943

French philosopher, mystic, and political activist. Wrote on labor, oppression, and spiritual life. Combined radical politics with religious mysticism.

1797 - 1883

American abolitionist and women's rights activist. Born into slavery, became a powerful orator known for her 'Ain't I a Woman?' speech.

1858 - 1919

26th President of the United States, Nobel Peace Prize laureate, trust-buster, conservationist, and Rough Rider. Champion of the strenuous life.

1588 - 1679

English philosopher best known for "Leviathan" (1651), which laid the foundation for modern political philosophy and social contract theory. Lived through the English Civil War, which deeply shaped hi...

1743 - 1826

Third President of the United States and principal author of the Declaration of Independence. Polymath, architect, and champion of individual liberty and limited government.

1737 - 1809

English-American political activist, author of Common Sense and The Rights of Man. Father of the American Revolution.

1694 - 1778

French Enlightenment writer and philosopher, author of Candide. Champion of reason and critic of religious intolerance.

1874 - 1965

British statesman, prime minister during World War II, and Nobel laureate in Literature. Known for wartime leadership and oratorical brilliance.