University College London Hospitals NHS Foundation Trust

Stories

Pre-surgery immunotherapy kept bowel cancer patients cancer-free for nearly three years

Co-lead and treating center for the NEOPRISM-CRC trial

A short course of immunotherapy before surgery kept every patient with a specific form of bowel cancer free of recurrence for nearly three years. In the NEOPRISM-CRC trial, 32 patients with MMR-deficient bowel cancer received pembrolizumab for up to nine weeks before surgery, instead of the usual post-operative chemotherapy.

Updated Oct 11

First real-time AI use in brain surgery protects patient's sight

New Capabilities

As of September 2026: Hosted the surgery at the National Hospital for Neurology and Neurosurgery

Rhys Hibbert, 48, went into surgery with an 11mm tumour pressing on the nerves that control his vision. He came out with what he calls 360-degree panoramic sight.

Updated Sep 7