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University of Barcelona

University of Barcelona

Research University

Appears in 2 stories

Stories

DNA hairpin therapy targets the gene behind high cholesterol

New Capabilities

Lead institution on the PPRH platform and HpE12 molecule

For two decades, lowering LDL cholesterol meant statins—daily pills that work for most but leave roughly one in five patients with muscle pain or liver enzyme changes severe enough to quit. On May 1, researchers at the University of Barcelona and Oregon Health & Science University published results on a short, engineered DNA molecule that silences the gene controlling how the liver clears LDL, cutting cholesterol by nearly 50 percent in mice after a single injection.

Updated May 7

Genomic study reveals predictable patterns in how animals conquered land

New Capabilities

Partner institution for study

In 1989, paleontologist Stephen Jay Gould argued that if you could rewind evolution and play it again, the results would be utterly different—humanity was a cosmic accident. A study published in Nature on November 12, 2025 offers the most comprehensive counterargument yet: when 11 different animal lineages independently crawled out of the water across 487 million years, they repeatedly evolved the same genetic solutions.

Updated Feb 10