Bing Ren

Corresponding author; scientific director and CEO of New York Genome Center; professor at Columbia University

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Last updated Sep 15, 2026

Stories

Study maps sweeping brain genome changes between ages 50 and 75

New Capabilities

As of September 2026: Leading the study and its follow-up work

The human brain reshapes how it reads its own genome between ages 50 and 75, according to a single-cell study published in Science. The brain's original immune cells decline during that window and are replaced by variants with stronger inflammatory signatures.

Updated Sep 15