Christopher Chase Bolt

Senior author listed last on the Cell paper

Appears in 1 story

Last updated Nov 1, 2026

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Retrotransposons write CAR genes into T cells inside living mice

New Capabilities

Leads the Gene Writers research effort

CAR-T therapy starts with a patient's T cells being removed, engineered in a lab and reinfused. A paper in Cell reports skipping the removal: engineered retrotransposons, delivered as RNA in lipid nanoparticles, inserted a receptor gene into T cells inside living mice.

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