Gabriel Ocana-Santero

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An AI agent chose a gene therapy and guided the needle into a live mouse's brain

Running follow-up tests on other AI models

On October 28, Gabriel Ocana-Santero, chief executive of the San Francisco startup Exin Therapeutics, posted an account of an experiment his team ran. An AI agent chose one of 19 gene-therapy candidates, picked the lateral entorhinal cortex as its target, derived injection coordinates from three published papers, and drove a needle 250 nanoliters into a live mouse's brain. A veterinarian opened the skull and held an emergency stop button the whole time.

Updated 1 hour ago

Notable Quotes

We've realized that we need to connect these agents to a lab to get the maximum value from them.

from An AI agent chose a gene therapy and guided the needle into a live mouse's brain · Updated 1 hour ago

I am not aware of an agent previously choosing a treatment and a brain target and then delivering it into a living mammal.

from An AI agent chose a gene therapy and guided the needle into a live mouse's brain · Updated 1 hour ago