Gordon D. Brown

New Capabilities

Contributed immunology expertise to the study

Cryptococcus neoformans kills roughly 180,000 people a year, most of them AIDS patients in sub-Saharan Africa. For a decade, the fungus's signature virulence trick was thought to be giant 'titan cells' — polyploid cells up to 100 µm across that resist immune attack. A new PLOS Biology paper shows the small end of the size spectrum may matter just as much.

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