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Jennifer R. Brown

Jennifer R. Brown

AMPLIFY Trial Principal Investigator; Director, CLL Center, Dana-Farber Cancer Institute

Appears in 1 story

Notable Quotes

"This is the first combination of a BTK inhibitor plus a BCL-2 inhibitor that we expect will receive FDA approval in the U.S." — Jennifer Brown, presenting AMPLIFY results at ASH 2024

Stories

Targeted drug combinations replace chemotherapy for common leukemia

New Capabilities

Led the Phase 3 AMPLIFY trial that supported the FDA approval

On February 20, 2026, the FDA approved venetoclax and acalabrutinib for chronic lymphocytic leukemia (CLL), the most common adult leukemia in Western countries, with roughly 23,000 new American cases each year. In a trial of 867 patients, 77% remained cancer-free at three years.

Updated May 29