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Kiran Bhaskar

Kiran Bhaskar

Professor, Department of Molecular Genetics & Microbiology, UNM School of Medicine

Appears in 1 story

Notable Quotes

"We set out to test whether stabilizing a specific type of ubiquitin chain would help clear toxic tau from neurons. Instead, we discovered something completely unexpected—that OTULIN acts as a master switch controlling whether tau is even produced in the first place." — Dr. Kiran Bhaskar

Stories

OTULIN discovery reveals master switch for tau production

New Capabilities

Co-Director, New Mexico Alzheimer's Disease Research Center

For three decades, billions of dollars, and hundreds of failed trials later, researchers pursued the wrong target. The University of New Mexico team found that OTULIN—an enzyme regulating inflammation—controls tau production, and disabling it in neurons eliminated tau while keeping cells healthy.

Updated May 22