Margaret McEntegart

Interventional cardiologist, NewYork-Presbyterian/Columbia University Irving Medical Center; trial discussant

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Last updated Nov 3, 2026

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Sirolimus-coated balloon is noninferior to drug-eluting stent at one year in TRANSFORM II

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Discussed TRANSFORM II at TCT 2026

For years, opening a narrowed coronary artery usually meant leaving a metal stent behind. TRANSFORM II tested a different approach: a balloon coated with sirolimus, a drug that limits scar tissue, used after the lesion is prepared and with a stent available as backup.

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