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AbbVie (Allergan)

AbbVie (Allergan)

Pharmaceutical company

Appears in 7 stories

Stories

Epcoritamab plus R-CHOP halves progression risk in first-line lymphoma trial

New Capabilities

Co-developer and co-commercializer of epcoritamab

AbbVie and Genmab said Monday that adding their bispecific antibody epcoritamab to the R-CHOP chemoimmunotherapy backbone cut the risk of disease progression or death by 51% in newly diagnosed diffuse large B-cell lymphoma (DLBCL). It is the first phase 3 trial of a bispecific antibody to beat R-CHOP in the frontline setting — a regimen that has anchored treatment for over 20 years.

Updated 4 days ago

FDA grants AbbVie's Temab-A two breakthrough therapy designations for colorectal and lung cancer

New Capabilities

Developer of Temab-A

The FDA granted AbbVie's experimental cancer drug Temab-A two breakthrough therapy designations on October 7. One covers colorectal cancer, the other non-small cell lung cancer. The designations speed up development and review for drugs that show early evidence of substantial improvement over existing therapies.

Updated 5 days ago

AbbVie Phase 2 results clear zumilokibart for Phase 3 eczema trials

New Capabilities

Owner of zumilokibart; running Phase 3 trials

Patients with moderate to severe atopic dermatitis on the mid-dose of zumilokibart hit 65.9% skin clearance at 16 weeks, versus 23.4% on placebo. AbbVie presented the Phase 2 results as a late-breaker at the European Academy of Dermatology and Venereology congress in Vienna on Sept. 30.

Updated Sep 30

Iambic launches Enchant v3 drug discovery model with 41 billion parameters

New Capabilities

Entered multi-year AI drug discovery collaboration with Iambic

Iambic released Enchant v3 on September 21, 2026: a 41-billion-parameter AI model trained on 4.5 trillion tokens of biomedical data, spanning everything from protein structures to clinical trial records. The same day, AbbVie signed a multi-year deal to use the model across immunology, neuroscience, and oncology.

Updated Sep 21

Targeted drug combinations replace chemotherapy for common leukemia

New Capabilities

Co-manufacturer of venetoclax (Venclexta); submitted the supplemental new drug application

On February 20, 2026, the FDA approved venetoclax and acalabrutinib for chronic lymphocytic leukemia (CLL), the most common adult leukemia in Western countries, with roughly 23,000 new American cases each year. In a trial of 867 patients, 77% remained cancer-free at three years.

Updated May 29

FDA approves AbbVie's Decnupaz for ultra-rare BPDCN blood cancer

New Capabilities

Decnupaz sponsor and manufacturer

The FDA approved AbbVie's Decnupaz on May 27 for blastic plasmacytoid dendritic cell neoplasm, an aggressive blood cancer. It strikes an estimated few hundred Americans a year. It's the second drug ever approved for the disease and the first doctors can start in an outpatient clinic.

Updated May 28

The race to replace reading glasses

New Capabilities

Marketing first-approved presbyopia drop Vuity

For 240 years, reading glasses have treated presbyopia—the gradual loss of near vision that affects nearly everyone over 45—unchanged since Benjamin Franklin invented bifocals in 1785. Two billion people worldwide still rely on reading glasses today. On January 29, 2026, the FDA approved YUVEZZI (carbachol and brimonidine tartrate ophthalmic solution), the first dual-agent eye drop for presbyopia.

Updated May 23