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Broad Institute of MIT and Harvard

Broad Institute of MIT and Harvard

Research Institute

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Machine learning reveals bacteria carry far more antiviral defenses than scientists assumed

New Capabilities

Home institution of the DefensePredictor team

Every major tool in genetic engineering — from the enzymes that cut DNA in the 1970s to CRISPR gene editing — started as a defense weapon bacteria use against viruses. Two research teams just revealed that bacteria carry roughly three times more of these weapons than anyone realized, identifying millions of antiviral proteins across tens of thousands of genomes using machine-learning models that can flag a new defense system in five minutes.

Updated 3 hours ago