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Novartis Pharmaceuticals

Novartis Pharmaceuticals

Pharmaceutical company

Appears in 15 stories · Last updated Nov 10, 2026

Stories

argenx buys a peptide chemistry company to build oral immunology drugs

Money Moves

Prior collaborator

Every medicine argenx sells today reaches patients by infusion or injection. On Nov. 9, 2026, the Dutch immunology company agreed to pay $550 million in cash for a Santa Cruz company whose chemistry is built to make pills instead.

Updated 1 hour ago

FDA approves first Factor XIa blood thinner for repeat strokes

New Capabilities

Testing an injectable Factor XIa antibody

Roughly a quarter of the 795,000 Americans who have a stroke each year have had one before. On Monday the Food and Drug Administration approved Sunharbo, a daily pill from Bayer that cuts the risk of a second ischemic stroke by 26% when taken alongside existing antiplatelet therapy.

Updated Yesterday

A heart drug cuts a major risk factor but not heart attacks

New Capabilities

Sponsor of Lp(a)HORIZON; halting pelacarsen development for cardiovascular disease

For five years, 8,322 people who had already survived a heart attack or stroke injected either pelacarsen or a placebo every month. The drug did what it was designed to do: it cut lipoprotein(a), a cholesterol-carrying particle, by 78%. Major cardiovascular events occurred in 12.3% of the pelacarsen group and 12.1% of the placebo group.

Updated 3 days ago

Novartis reports tumors in children treated with Zolgensma gene therapy

New Capabilities

Maker of Zolgensma; reporting the tumor cases to regulators

Nine children who received Zolgensma, a one-time gene therapy for spinal muscular atrophy, later developed tumors. In two of the three cases tested, Novartis found evidence the virus used to deliver the treatment had inserted itself into the patient's DNA.

Updated 4 days ago

Vanda's anxiety drug VQW-765 fails late-stage trial, program on hold

New Capabilities

Original developer of VQW-765 and licensor to Vanda

Vanda Pharmaceuticals' experimental anxiety drug failed its 546-patient Phase III trial, and the company has put the program on hold. VQW-765 matched placebo on a public-speaking stress test in adults with social anxiety disorder.

Updated Oct 19

Novartis licenses Abogen's mRNA T-cell engager in up to $7.8 billion deal

Money Moves

As of October 2026: Licensee; secures exclusive worldwide rights to ABO2203 and option rights on other Abogen RNA programs

Novartis agreed to pay up to $7.8 billion for rights to Chinese biotech Abogen's mRNA therapeutics. The deal includes a $575 million upfront payment and an exclusive worldwide license to ABO2203, the first mRNA-encoded T-cell engager to reach clinical testing in autoimmune disease.

Updated Oct 2

Kyverna touts year-long miv-cel data as Novartis, Bristol Myers pause autoimmune CAR-T trials

New Capabilities

As of September 2026: Paused three autoimmune CAR-T trials after participant deaths

Novartis paused its autoimmune CAR-T trials this month after three patients died from a severe immune reaction, and Bristol Myers paused its own over similar inflammatory events. The same week, Kyverna Therapeutics released 12 months of follow-up data on miv-cel, its rival therapy, reporting sustained improvement in stiff person syndrome patients with no high-grade immune toxicity.

Updated Sep 24

Roche's sefaxersen meets phase 3 goal, joining IgAN market battle with Novartis

New Capabilities

As of September 2026: Competitor; markets Fabhalta (iptacopan) for IgAN

Roche's experimental IgA nephropathy drug sefaxersen met its phase 3 primary endpoint on September 23, cutting proteinuria versus placebo at 37 weeks in the IMAgINATION study. The result, from a prespecified interim look, was strong enough that Roche is taking it to health authorities and planning a medical meeting presentation.

Updated Sep 23

Amgen's dazodalibep clears phase 3 Sjögren's trial

New Capabilities

As of September 2026: Rival with ianalumab under FDA review

Sjögren's disease has no approved treatment in the US. Amgen just moved a step closer to ending that.

Updated Sep 22

Telix acquires isotope maker ITM in deal worth up to $2.35 billion

Money Moves

As of September 2026: Competitor and ITM's largest lutetium-177 customer

Telix Pharmaceuticals, an Australian maker of cancer imaging and treatment agents, agreed on September 21 to buy German isotope producer ITM Isotope Technologies Munich. The deal is worth up to $2.35 billion all-in, with $1.65 billion paid upfront, most of it in Telix shares.

Updated Sep 21

The Alexandria Files for Liquor License at San Diego's Campus Point Megacampus

Built World

As of September 2026: Investing $1.1B into new Campus Point headquarters

A venue called The Alexandria at 4150 Campus Point Court in San Diego applied for a California liquor license. The application appeared on the state's ABC licensing list on September 18, 2026.

Updated Sep 18

Novartis\' $12B del-desiran flops in crucial phase 3 trial

Money Moves

As of September 2026: Facing investor pressure after two phase 3 failures

Novartis' experimental muscle-disease drug del-desiran failed its phase 3 Harbor trial, missing the primary endpoint and sending shares down. The drug was the centerpiece of the company's $12 billion acquisition of Avidity Biosciences, which closed last year.

Updated Sep 8

The gene therapy revolution: from fatal setback to living cures

New Capabilities

As of July 2026: Manufacturer of Kymriah, first FDA-approved CAR-T therapy

Gene therapy killed Jesse Gelsinger in 1999. His death triggered FDA shutdowns and nearly ended the field.

Updated Jul 3

Merck races to rebuild its drug portfolio before Keytruda's patent expires

Money Moves

As of May 2026: Incumbent competitor in CML market with Scemblix

Keytruda, the world's best-selling drug, generated $31.7 billion for Merck in 2025 — roughly 40% of the company's total revenue. Its key U.S. patents expire in 2028, and when they do, cheaper copies will enter the market and that revenue will begin to evaporate. Merck has now spent over $25 billion on three acquisitions in nine months to build the portfolio that will need to replace it.

Updated May 30

The race to protect 27 million Americans from accidental food allergen exposure

Money Moves

As of May 2026: Competitor; developing oral BTK inhibitor for food allergy

For decades, the 27 million American adults and children with food allergies had one option: avoid the allergen and carry an EpiPen. That changed in February 2024 when the FDA approved Xolair as the first drug to reduce allergic reactions—including anaphylaxis—from accidental exposure to multiple foods.

Updated May 22