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Dana-Farber Cancer Institute

Dana-Farber Cancer Institute

Cancer research and treatment center

Appears in 5 stories · Last updated Oct 26, 2026

Stories

Apalutamide before and after prostate surgery reduces recurrence risk

New Capabilities

Co-led the PROTEUS substudy with principal investigator Mary-Ellen Taplin

Apalutamide taken for six months before and after prostate cancer surgery cut the risk of recurrence or death by 62% compared with surgery alone in a 408-patient substudy of the PROTEUS trial. Johnson & Johnson reported the results on Oct. 24, 2026; they were presented at the ESMO Congress in Madrid and accepted for publication by European Urology.

Updated Oct 26

Bispecific antibody combo extends survival in small cell lung cancer

New Capabilities

Home institution of the presenting investigator for DeLLphi-305

Small cell lung cancer that has spread through the chest and beyond has held median survival near a year for decades. A phase 3 trial presented Oct. 24 at the ESMO Congress raised that to 21.1 months, about eight months longer than the comparison arm.

Updated Oct 26

Dana-Farber breaks ground on dedicated cancer hospital in Boston

Built World

Building its first dedicated inpatient hospital

Dana-Farber Cancer Institute broke ground on Oct. 19 on a 300-bed hospital built solely for cancer patients, the first inpatient facility of its kind in the Boston region. The $1.68 billion Lavine Bekenstein Cancer Hospital, set to open in 2031 on the former Joslin Diabetes Center site, will have 30 intensive care beds and four floors with specialized air protection for patients with weakened immune systems.

Updated Oct 20

IL-21 mimic converts transient KRAS inhibitor responses into durable remissions in pancreatic cancer

New Capabilities

As of September 2026: Hosted the study

Pancreatic cancer ignores nearly every approved immunotherapy, and the new KRAS inhibitors shrink tumors only until resistance emerges. A study published online this week in Cell pairs those inhibitors with a designer mimic of the immune signal IL-21 — and in mice, the combination cleared pancreatic tumors and kept them clear for months.

Updated Sep 24

Teclistamab shows deep remissions in high-risk smoldering myeloma trial

New Capabilities

As of September 2026: Led the ImmunoPRISM trial

Doctors at Dana-Farber Cancer Institute gave teclistamab, a bispecific antibody already approved for advanced myeloma, to 45 patients with high-risk smoldering multiple myeloma. Complete remission followed in 77.8% of them.

Updated Sep 14