West Africa Ebola epidemic (2014-2016)
The largest Ebola outbreak in history began in Guinea and spread to Sierra Leone and Liberia, killing more than 11,000 people. It was the Zaire strain, which later gained an approved vaccine. The virus reached major cities and overwhelmed underfunded health systems across three countries.
Closed borders, overwhelmed health systems, and more than 11,000 deaths across three countries.
Spurred development of Zaire-strain vaccines and treatments and led to reforms in global outbreak response.
The current outbreak is on track to approach this scale if containment fails, but it involves a strain without approved tools.
