Heartland virus discovery (2009-2012)
Two Missouri farmers were hospitalized in 2009 with fever, fatigue, and low platelets, and no known cause. The CDC identified the cause as a new phlebovirus, named Heartland virus, and later confirmed the Lone Star tick as its vector.
Heartland virus is now recognized across the eastern and central US, with dozens of cases reported.
It expanded the known range of tick-borne disease and prompted wider tick surveillance.
The same pattern — an unexplained tick-borne fever yielding a new virus — produced ALTNV, and Heartland's later spread shows how a newly identified virus can turn out to be far more widespread than first thought.
