Toronto clinical lung perfusion trial (2011)
Surgeon Shaf Keshavjee and colleagues at Toronto General Hospital perfused high-risk donor lungs and transplanted those that passed. They reported the results in the New England Journal of Medicine.
Perfused marginal lungs showed outcomes close to standard donor lungs.
The study turned ex vivo lung perfusion from a lab idea into accepted clinical practice.
It is the clinical evidence base that approvals like LungFX rest on.
