Tower Nomination Rejected (1989)
John Tower, George H.W. Bush's nominee for Defense Secretary, became the last Cabinet nominee rejected by the Senate. The Senate voted 53-47 against confirmation after allegations of excessive drinking and womanizing. Nine Republicans joined Democrats in opposition. Tower remains the most recent outright rejection of a Cabinet nominee.
Bush nominated Dick Cheney instead, who was confirmed unanimously 92-0.
Established that Senate would reject nominees with serious personal conduct issues, though this standard has weakened over time.
Matt Gaetz withdrew facing similar personal conduct allegations before reaching a confirmation vote. The Tower precedent may have convinced Gaetz and Trump that outright rejection was possible, prompting withdrawal strategy instead.
