AlphaFold2 (2020)
At the 2020 CASP14 assessment, DeepMind's AlphaFold2 predicted protein structures with accuracy rivaling experimental methods. It showed a neural network could learn biological structure from data rather than simulate it from first principles.
AlphaFold2 was released in 2021 and quickly became a standard tool for biologists.
Protein structure prediction shifted from a laborious experimental task to a computational one, and DeepMind later released predicted structures for nearly all known proteins.
WorldParticle applies a similar learned-dynamics idea to protein motion over time, and its authors aim for a comparable shift in simulation.
