ENCODE project (2012)
The ENCODE project published a suite of papers mapping functional elements across the human genome, assigning biochemical function to about 80% of it. It gave researchers a parts list for the genome beyond protein-coding genes.
Directed disease research toward non-coding DNA and regulatory regions.
Became a standard reference resource for interpreting genome-wide association studies.
ENCODE mapped what DNA does; this atlas maps which human-specific changes actually alter gene activity.
