Smallpox Eradication (1967-1980)
WHO launched intensive global campaign using ring vaccination strategy, tracking every outbreak, and vaccinating contacts. Disease declared eradicated in 1980—the only human infectious disease ever completely eliminated. Last natural case occurred in Somalia in 1977.
WHO declared world free of smallpox on May 8, 1980.
Saves over $1 billion annually since 1980; proved disease eradication feasible with sustained commitment.
Trachoma could become second disease eliminated globally as public health problem, but unlike smallpox requires behavior change (facial cleanliness, water access) not just medical intervention, making complete eradication more complex.
